I have used Openbravo ERP a lot, recently with AWS Aurora for PostgreSQL, which is great for large customers.
Interested to know if ERPNext can work with AWS Aurora for MySQL. AWS Aurora has a lot of traction in U.S. - IT-savvy mid to large customers increasingly rely on it for data availability and scalability, so being able to plug into what they are already using it helps with convincing customers to pilot an enterprise open source app like ERPNext.
It does work with Amazon RDS, which is functionally equivalent, but has different pricing scheme, which is part of the appeal of Aurora. If you’re really only using your ERP during business hours, why pay for cycles on the hours you’re not?