Assign Item Attributes in Sales Orders and Invoices

Our Company deals in Printing, Graphic design and Digital Marketing but we have a lot of product customisations when it comes to Printing.

I created Items and Item Attributes. Am wondering whether I can be able to select items and then assign them specific attributes in sales orders and invoices?
We have a lot of Items, and Item Attributes each with numerous values, creating Item Variants for each combination will end up having 1000’s of items which might be hard to identify.

Any advice or help is highly appreciated. Thanks.

did you find a solution to this?