AWS Server Configuration Suggestion

According to Frappe / ERPNext architecture do you have any configuration suggestion for a small medium organization. Suppose

  1. 10 user daily 100 transaction*
  2. 20 user daily 400 transaction
  3. Above 1 and 2 's user could divided into 2 multi tenant install.
  4. Or any general suggestion based on user.

Here transaction means whether user is creating sales order, purchase order or journal entry.