I am also very interested in this. Ecommerce is why I began using ErpNext. I have an erpnext version 14 instance running on GCP and I was planning to move to version 15 towards the end of this year.
There has been some discussions with open source Ecommerce tool integrations before in this forum. I see @UC77 also in that thread. Great to see more people are excited about this. With MedusaJS V2, I am more hopeful about this possibility.
I concur with the idea here, to have 2 distinct systems for ecommerce and erp functionality in case something breakes.
ERPNext is great at what it does, has a very comprehensive list of fuctionalities that mostly work without bugs. Great for what you would expect from an ERP system. Great accounting, inventory, HR and so on… If Medusa is just that for Ecommerce, I think synergy we can get out of this is massive.
I am not a skilled programmer, I actually develop hardware but I am currently following @buildwithhussain Frappe Developer Bootcamp on youtube. After I finish it I will explore deveoping custom integrations and using the API.