Twilio Integration Notifucation Error

Failed to Send Notification
Erpnext Error
Traceback with variables (most recent call last):
File “apps/frappe/frappe/email/doctype/notification/notification.py”, line 140, in send
self.create_system_notification(doc, context)
self = <SendNotification: tasahel whatsapp>
doc = <WebsiteOrder: WEB-ORD-32027>
context = {‘doc’: <WebsiteOrder: WEB-ORD-32027>, ‘alert’: <SendNotification: tasahel whatsapp>, ‘comments’: None}
File “apps/frappe/frappe/email/doctype/notification/notification.py”, line 174, in create_system_notification
if “{” in subject:
self = <SendNotification: tasahel whatsapp>
doc = <WebsiteOrder: WEB-ORD-32027>
context = {‘doc’: <WebsiteOrder: WEB-ORD-32027>, ‘alert’: <SendNotification: tasahel whatsapp>, ‘comments’: None}
subject = None
builtins.TypeError: argument of type ‘NoneType’ is not iterable

Twilio Error
Twilio was unable to fetch content from: http://139.144.181.182:8000/api/method/twilio_integration.twilio_integration.api.whatsapp_message_status_callback
Error: Failed to connect to ip 139.144.181.182: No route to host: /139.144.181.182:8000
Account SID: AC1874ca79a16312b64e4849dc8fa16d7e
SID: SM274812463b52743ab8c20d5c30b2818d
Request ID: 3d5ab7f8-0fed-4324-adcb-a469478b5366
Remote Host: 139.144.181.182
Request Method: POST
Request URI: http://139.144.181.182:8000/api/method/twilio_integration.twilio_integration.api.whatsapp_message_status_callback
URL Fragment: true

check this:
https://discuss.frappe.io/t/url-configuration-issue/88738/8?u=muhannad_abdeljawwad